- 1:30 - 3 p.m.
- 10:00 a.m. - 12:30 p.m.
- 11:00 a.m. - noon
- CHEM 312 Interdisciplinary Chemistry Project Lab
- CHEM 323 Foundations of Biochemistry
PhD University of Wisconsin Madison
BS Centre College
I graduated from Centre College, a small liberal arts college in Kentucky, in 2005 with a BS in Biochemistry & Molecular Biology. In graduate school at the University of Wisconsin-Madison, I started tinkering with biological machines. I earned a PhD in Biomolecular Chemistry in 2010 and then did postdoctoral research in biophysics at Vanderbilt University until 2014. After nine years devoted to research, I missed the classroom and the close student-faculty interaction at a liberal arts college, so I spent two years teaching general, biological, and biophysical chemistry at Carleton College in Minnesota. In 2016, I joined the faculty at UNCA where I can fulfill my interest in teaching and getting students hooked on research.
I live in Mills River with my wife and three children. Outside of UNCA, I enjoy drinking good beer, exploring the mountains, and dabbling in woodworking.
My research centers around the question of how the energy stored in an electrochemical gradient is used to power a biological nanomachine. My students and I are currently focusing on ATP synthase, the proton-driven rotary motor responsible for making most of the ATP (biological energy currency) on the planet. We are working to elucidate the mechanism by which ion movement through the membrane-embedded stator subunit generates torque on the rotor.
Current projects include:
1. Probing the importance of amino acids at the rotor-stator interface using site-directed mutagenesis and biochemical assays.
2. Uncovering structural dynamics within the stator subunit using electron paramagnetic resonance spectroscopy.
3. Optimizing a reconstituted proteoliposome system to study the effects of lipid composition on ion transport.